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Mar

08

New Targets Revealed for Treating Adult Blood Cancer with CRISPR Editing

CDK6 inhibitors/antagonists

New Targets Revealed for Treating Adult Blood Cancer with CRISPR Editing

Adult T-cell leukemia/lymphoma (ATL or ATLL) is a rare type of non-Hodgkin lymphoma that can be found in the blood (leukemia), lymph nodes (lymphoma), skin, or multiple areas of the body. ATLL has been linked to infection with the human T-cell lymphotropic virus type 1 (HTLV-1); however, less than five percent of individuals with HTLV-1 will develop ATLL.

Feb

10

Small Molecule Compounds and the VEGF Signaling Pathway

vegf-pathway

Small Molecule Compounds and the VEGF Signaling Pathway

Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by fibroblasts that stimulate the formation of blood vessels. Vascular endothelial growth factors are important signaling proteins involved in both vasculogenesis (the de novo formation of the embryonic circulatory system) and angiogenesis (the growth of blood vessels from pre-existing vasculature).

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